Searchable abstracts of presentations at key conferences in endocrinology

ea0016p563 | Obesity | ECE2008

ERK1/2 MAPKs and Wnt signaling pathways are independently involved in adipocyte-mediated aldosterone secretion

Vleugels Kim , Ehrhart-Bornstein Monika , Bornstein Stefan R , Krug Alexander W

One important risk factor for the development of arterial hypertension is abdominal obesity. Aldosterone, secreted by adrenocortical cells, promotes sodium and water retention and by that regulates blood pressure homeostasis. Increased serum aldosterone levels have been linked to the development of obesity hypertension. Therefore, identifying the link between obesity and increased aldosterone secretion is of high importance for the management of obesity hypertension.<p cla...